Drugs for risk factors

Drugs for common risk factors of diseases

Outcome trait

 

P-value threshold: 1e-5
   

 

 

Summary

This view attempts to find potential drugs for a disease outcome via SNPs that influence causal risk factors for that outcome. For a given disease we find potential causal risk factors. For each of those risk factors we take robustly associated genetic variants and map those to gene (this is currently just a physical distance mapping). Drugs that target the products of those genes are then identified using data from Open Targets.

Data sources

  • Gene to drug mappings are taken from Open Targets using their API
  • Causal estimates are from MR-EvE (Hemani et al, Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome, bioRxiv 10.1101/173682)
  • SNP-trait assocaitions are from the IEU GWAS database

How to use

Enter your disease outcome in the Disease trait text box, use the slider to select a p-value threshold for the strength of MR causal evidence, then click Search.

Top results are presented in the Network plot tab, with full results searchable in the Table tab. The Query tab provides information to enable you to download full results using the API.

Examples

 Displays 150 / 4101 paths

 

assoc_trait.id assoc_trait.trait drug.label gene.name mr.estimate mr.method mr.moescore mr.p mr.se mr.selection snp.name trait.id trait.trait
UKB-a:393 Maximum heart rate during fitness test AMLODIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test FELODIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test VERAPAMIL CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test NIFEDIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test NICARDIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test CLEVIDIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test DILTIAZEM CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test DRONEDARONE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test NIMODIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test BEPRIDIL CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test CINNARIZINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test NISOLDIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test SULOCTIDIL CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test ISRADIPINE CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test IMAGABALIN CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test ATAGABALIN CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:393 Maximum heart rate during fitness test AZD1305 CACNA1C -0.218755 FE IVW 1.00 0.000000e+00 0.005812 DF rs7314860 6 Coronary heart disease
UKB-a:20 Exposure to tobacco smoke outside home ROMIDEPSIN HDAC9 0.550906 FE IVW 1.00 0.000000e+00 0.008674 DF rs35614472 7 Coronary heart disease
UKB-a:20 Exposure to tobacco smoke outside home PANOBINOSTAT HDAC9 0.550906 FE IVW 1.00 0.000000e+00 0.008674 DF rs35614472 7 Coronary heart disease
UKB-a:20 Exposure to tobacco smoke outside home BELINOSTAT HDAC9 0.550906 FE IVW 1.00 0.000000e+00 0.008674 DF rs35614472 7 Coronary heart disease
UKB-a:20 Exposure to tobacco smoke outside home TACEDINALINE HDAC9 0.550906 FE IVW 1.00 0.000000e+00 0.008674 DF rs35614472 7 Coronary heart disease
UKB-a:20 Exposure to tobacco smoke outside home ENTINOSTAT HDAC9 0.550906 FE IVW 1.00 0.000000e+00 0.008674 DF rs35614472 7 Coronary heart disease
UKB-a:20 Exposure to tobacco smoke outside home FIMEPINOSTAT HDAC9 0.550906 FE IVW 1.00 0.000000e+00 0.008674 DF rs35614472 7 Coronary heart disease
UKB-a:20 Exposure to tobacco smoke outside home CUDC-101 HDAC9 0.550906 FE IVW 1.00 0.000000e+00 0.008674 DF rs35614472 7 Coronary heart disease
UKB-a:114 Non-cancer illness code self-reported: hypertrophic cardiomyopathy (hcm / hocm) PF-03732010 CDH3 -25.411017 FE IVW 1.00 0.000000e+00 0.024798 DF rs140946413 8 Coronary heart disease
918 Phosphatidylcholine and other cholines EVOLOCUMAB PCSK9 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs11591147 8 Coronary heart disease
918 Phosphatidylcholine and other cholines ALIROCUMAB PCSK9 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs11591147 8 Coronary heart disease
918 Phosphatidylcholine and other cholines BOCOCIZUMAB PCSK9 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs11591147 8 Coronary heart disease
918 Phosphatidylcholine and other cholines RALPANCIZUMAB PCSK9 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs11591147 8 Coronary heart disease
918 Phosphatidylcholine and other cholines HMG COA REDUCTASE INHIBITORS CETP 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs821840 8 Coronary heart disease
918 Phosphatidylcholine and other cholines DALCETRAPIB CETP 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs821840 8 Coronary heart disease
918 Phosphatidylcholine and other cholines EVACETRAPIB CETP 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs821840 8 Coronary heart disease
918 Phosphatidylcholine and other cholines ANACETRAPIB CETP 0.049793 FE IVW 1.00 6.322359e-289 0.001371 DF rs821840 8 Coronary heart disease
501 Pyroglutamine* CARGLUMIC ACID CPS1 -0.566019 FE IVW 1.00 3.084988e-211 0.018248 DF rs715 6 Coronary heart disease
501 Pyroglutamine* VALPROIC ACID CPS1 -0.566019 FE IVW 1.00 3.084988e-211 0.018248 DF rs715 6 Coronary heart disease
496 X-11317 HMG COA REDUCTASE INHIBITORS CETP -1.122637 FE IVW 1.00 5.846781e-209 0.036392 DF rs7499892 7 Coronary heart disease
496 X-11317 DALCETRAPIB CETP -1.122637 FE IVW 1.00 5.846781e-209 0.036392 DF rs7499892 7 Coronary heart disease
496 X-11317 EVACETRAPIB CETP -1.122637 FE IVW 1.00 5.846781e-209 0.036392 DF rs7499892 7 Coronary heart disease
496 X-11317 ANACETRAPIB CETP -1.122637 FE IVW 1.00 5.846781e-209 0.036392 DF rs7499892 7 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks TRIAMCINOLONE CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks FLUTICASONE/SALMETEROL CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks FLUTICASONE PROPIONATE CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks BUDESONIDE CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks ONO-2333MS CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks SSR125543 CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks PEXACERFONT CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks VERUCERFONT CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:244 Frequency of tenseness / restlessness in last 2 weeks EMICERFONT CRHR1 -0.475654 FE IVW 1.00 3.909937e-96 0.022863 DF rs62055701 6 Coronary heart disease
UKB-a:452 Medication for pain relief constipation heartburn: Aspirin HMG COA REDUCTASE INHIBITORS LPA -1.985062 FE IVW 1.00 6.999204e-82 0.103567 DF rs10455872 8 Coronary heart disease
721 X-14208--phenylalanylserine CAPTOPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine RAMIPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine FOSINOPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine BENAZEPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine LISINOPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine QUINAPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine TRANDOLAPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine PERINDOPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine CAPTOPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine ENALAPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine CILAZAPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine MOEXIPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine SPIRAPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine ENALAPRILAT ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
721 X-14208--phenylalanylserine CAPTOPRIL ACE 0.208598 FE IVW 1.00 3.022203e-72 0.011604 DF rs4362 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease HMG COA REDUCTASE INHIBITORS LPA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs55730499 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease ATORVASTATIN LDLR 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs6511720 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease AMBRISENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease BOSENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease MACITENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease DARUSENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease ATRASENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease SPARSENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease CLAZOSENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease SITAXENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease ZIBOTENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease TEZOSENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease AVOSENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:201 Illnesses of father: Heart disease NEBENTAN EDNRA 8.245482 FE IVW 0.86 7.438696e-72 0.459983 Tophits rs72957606 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication SULFONAMIDES TCF7L2 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs61872784 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication LEFLUNOMIDE DHODH 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs11648003 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication TERIFLUNOMIDE DHODH 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs11648003 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication ATORVASTATIN LDLR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs8106503 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication ATORVASTATIN LDLR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs2738447 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication ATORVASTATIN APOE 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs7412 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication ATORVASTATIN APOE 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs1081105 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication EVOLOCUMAB PCSK9 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs11591147 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication ALIROCUMAB PCSK9 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs11591147 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication BOCOCIZUMAB PCSK9 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs11591147 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication RALPANCIZUMAB PCSK9 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs11591147 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication HMG COA REDUCTASE INHIBITORS HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication SIMVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication ATORVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication ROSUVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication PRAVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication FLUVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication PITAVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication CERIVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication LOVASTATIN HMGCR 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs12916 7 Coronary heart disease
UKB-a:448 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Cholesterol lowering medication HMG COA REDUCTASE INHIBITORS LPA 3.633325 FE IVW 0.93 2.235785e-71 0.203384 HF rs74617384 7 Coronary heart disease
770 HOMA-B TASIMELTEON MTNR1B -0.234726 FE IVW 1.00 2.594709e-69 0.013339 DF rs10830963 6 Coronary heart disease
770 HOMA-B AGOMELATINE MTNR1B -0.234726 FE IVW 1.00 2.594709e-69 0.013339 DF rs10830963 6 Coronary heart disease
770 HOMA-B RAMELTEON MTNR1B -0.234726 FE IVW 1.00 2.594709e-69 0.013339 DF rs10830963 6 Coronary heart disease
1079 Zinc ACETAZOLAMIDE CA1 0.060036 FE IVW 1.00 1.466650e-57 0.003754 DF rs1532423 7 Coronary heart disease
1079 Zinc METHAZOLAMIDE CA1 0.060036 FE IVW 1.00 1.466650e-57 0.003754 DF rs1532423 7 Coronary heart disease
1079 Zinc DICHLORPHENAMIDE CA1 0.060036 FE IVW 1.00 1.466650e-57 0.003754 DF rs1532423 7 Coronary heart disease
1079 Zinc POLMACOXIB CA1 0.060036 FE IVW 1.00 1.466650e-57 0.003754 DF rs1532423 7 Coronary heart disease
1079 Zinc METHOCARBAMOL CA1 0.060036 FE IVW 1.00 1.466650e-57 0.003754 DF rs1532423 7 Coronary heart disease
798 Myocardial infarction COLLAGENASE CLOSTRIDIUM HISTOLYTICUM COL4A2 0.974757 Simple median 0.81 2.809606e-57 0.061110 Tophits rs4773141 7 Coronary heart disease
798 Myocardial infarction OCRIPLASMIN COL4A2 0.974757 Simple median 0.81 2.809606e-57 0.061110 Tophits rs4773141 7 Coronary heart disease
798 Myocardial infarction COLLAGENASE CLOSTRIDIUM HISTOLYTICUM COL4A1 0.974757 Simple median 0.81 2.809606e-57 0.061110 Tophits rs4773141 7 Coronary heart disease
798 Myocardial infarction OCRIPLASMIN COL4A1 0.974757 Simple median 0.81 2.809606e-57 0.061110 Tophits rs4773141 7 Coronary heart disease
798 Myocardial infarction HMG COA REDUCTASE INHIBITORS LPA 0.974757 Simple median 0.81 2.809606e-57 0.061110 Tophits rs10455872 7 Coronary heart disease
880 Total cholesterol in large LDL EVOLOCUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs553741 7 Coronary heart disease
880 Total cholesterol in large LDL ALIROCUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs553741 7 Coronary heart disease
880 Total cholesterol in large LDL BOCOCIZUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs553741 7 Coronary heart disease
880 Total cholesterol in large LDL RALPANCIZUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs553741 7 Coronary heart disease
880 Total cholesterol in large LDL EVOLOCUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs11591147 7 Coronary heart disease
880 Total cholesterol in large LDL ALIROCUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs11591147 7 Coronary heart disease
880 Total cholesterol in large LDL BOCOCIZUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs11591147 7 Coronary heart disease
880 Total cholesterol in large LDL RALPANCIZUMAB PCSK9 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs11591147 7 Coronary heart disease
880 Total cholesterol in large LDL ATORVASTATIN LDLR 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs137992968 7 Coronary heart disease
880 Total cholesterol in large LDL ATORVASTATIN APOE 0.387681 FE IVW 0.86 4.362363e-56 0.024570 Tophits rs7412 7 Coronary heart disease
883 Total lipids in large LDL EVOLOCUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs553741 7 Coronary heart disease
883 Total lipids in large LDL ALIROCUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs553741 7 Coronary heart disease
883 Total lipids in large LDL BOCOCIZUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs553741 7 Coronary heart disease
883 Total lipids in large LDL RALPANCIZUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs553741 7 Coronary heart disease
883 Total lipids in large LDL EVOLOCUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs11591147 7 Coronary heart disease
883 Total lipids in large LDL ALIROCUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs11591147 7 Coronary heart disease
883 Total lipids in large LDL BOCOCIZUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs11591147 7 Coronary heart disease
883 Total lipids in large LDL RALPANCIZUMAB PCSK9 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs11591147 7 Coronary heart disease
883 Total lipids in large LDL ATORVASTATIN LDLR 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs137992968 7 Coronary heart disease
883 Total lipids in large LDL ATORVASTATIN APOE 0.373197 FE IVW 0.85 3.267894e-55 0.023845 Tophits rs7412 7 Coronary heart disease
884 Concentration of large LDL particles ATORVASTATIN APOE 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs7412 7 Coronary heart disease
884 Concentration of large LDL particles ATORVASTATIN LDLR 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs137992968 7 Coronary heart disease
884 Concentration of large LDL particles EVOLOCUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs11591147 7 Coronary heart disease
884 Concentration of large LDL particles ALIROCUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs11591147 7 Coronary heart disease
884 Concentration of large LDL particles BOCOCIZUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs11591147 7 Coronary heart disease
884 Concentration of large LDL particles RALPANCIZUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs11591147 7 Coronary heart disease
884 Concentration of large LDL particles EVOLOCUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs553741 7 Coronary heart disease
884 Concentration of large LDL particles ALIROCUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs553741 7 Coronary heart disease
884 Concentration of large LDL particles BOCOCIZUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs553741 7 Coronary heart disease
884 Concentration of large LDL particles RALPANCIZUMAB PCSK9 0.372811 FE IVW 0.84 2.295510e-53 0.024243 Tophits rs553741 7 Coronary heart disease
UKB-a:445 Blood clot DVT bronchitis emphysema asthma rhinitis eczema allergy diagnosed by doctor: Blood clot in the lung FIBRINOLYSIN, HUMAN FGA -13.489930 FE IVW 1.00 8.698254e-46 0.949752 DF rs6050 8 Coronary heart disease
UKB-a:537 Diagnoses - main ICD10: I80 Phlebitis and thrombophlebitis FIBRINOLYSIN, HUMAN FGG -16.272502 FE IVW 1.00 7.066078e-34 1.341183 DF rs2066861 6 Coronary heart disease
UKB-a:537 Diagnoses - main ICD10: I80 Phlebitis and thrombophlebitis APROTININ KLKB1 -16.272502 FE IVW 1.00 7.066078e-34 1.341183 DF rs4253304 6 Coronary heart disease
UKB-a:537 Diagnoses - main ICD10: I80 Phlebitis and thrombophlebitis ECALLANTIDE KLKB1 -16.272502 FE IVW 1.00 7.066078e-34 1.341183 DF rs4253304 6 Coronary heart disease
UKB-a:537 Diagnoses - main ICD10: I80 Phlebitis and thrombophlebitis LANADELUMAB KLKB1 -16.272502 FE IVW 1.00 7.066078e-34 1.341183 DF rs4253304 6 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication EVOLOCUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs693668 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ALIROCUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs693668 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication BOCOCIZUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs693668 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication RALPANCIZUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs693668 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication EVOLOCUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs11591147 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ALIROCUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs11591147 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication BOCOCIZUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs11591147 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication RALPANCIZUMAB PCSK9 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs11591147 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ATORVASTATIN LDLR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs6511720 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ATORVASTATIN APOE 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs7412 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ATORVASTATIN LDLR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs2738447 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication LY2940094 OPRL1 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs8126001 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication CEBRANOPADOL OPRL1 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs8126001 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ATORVASTATIN APOE 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs1081105 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication HMG COA REDUCTASE INHIBITORS HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication SIMVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ATORVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication ROSUVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication PRAVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication FLUVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication PITAVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication CERIVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication LOVASTATIN HMGCR 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs12916 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication HMG COA REDUCTASE INHIBITORS LPA 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs55730499 7 Coronary heart disease
UKB-a:488 Medication for cholesterol blood pressure or diabetes: Cholesterol lowering medication SULFONAMIDES TCF7L2 2.978396 Weighted median 0.94 7.421102e-34 0.245561 HF rs35198068 7 Coronary heart disease
925 Total lipids in small LDL HMG COA REDUCTASE INHIBITORS HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL SIMVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL ATORVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL ROSUVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL PRAVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL FLUVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL PITAVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL CERIVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL LOVASTATIN HMGCR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs12916 7 Coronary heart disease
925 Total lipids in small LDL EVOLOCUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs11591147 7 Coronary heart disease
925 Total lipids in small LDL ALIROCUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs11591147 7 Coronary heart disease
925 Total lipids in small LDL BOCOCIZUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs11591147 7 Coronary heart disease
925 Total lipids in small LDL RALPANCIZUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs11591147 7 Coronary heart disease
925 Total lipids in small LDL EVOLOCUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs2495477 7 Coronary heart disease
925 Total lipids in small LDL ALIROCUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs2495477 7 Coronary heart disease
925 Total lipids in small LDL BOCOCIZUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs2495477 7 Coronary heart disease
925 Total lipids in small LDL RALPANCIZUMAB PCSK9 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs2495477 7 Coronary heart disease
925 Total lipids in small LDL ATORVASTATIN APOE 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs7412 7 Coronary heart disease
925 Total lipids in small LDL ATORVASTATIN LDLR 0.370751 FE IVW 0.77 1.149370e-32 0.031149 DF + HF rs137992968 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ATORVASTATIN LDLR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs6511720 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ATORVASTATIN LDLR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs2738447 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol SULFONAMIDES TCF7L2 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs56299331 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol PROBUCOL ABCA1 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs1883025 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ATORVASTATIN APOE 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs112019714 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ATORVASTATIN APOE 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs7412 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol EVOLOCUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs11591147 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ALIROCUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs11591147 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol BOCOCIZUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs11591147 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol RALPANCIZUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs11591147 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol EVOLOCUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs472495 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ALIROCUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs472495 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol BOCOCIZUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs472495 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol RALPANCIZUMAB PCSK9 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs472495 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol HMG COA REDUCTASE INHIBITORS HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol SIMVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ATORVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol ROSUVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol PRAVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol FLUVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol PITAVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol CERIVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol LOVASTATIN HMGCR 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs12916 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol HMG COA REDUCTASE INHIBITORS LPA 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs74617384 7 Coronary heart disease
UKB-a:108 Non-cancer illness code self-reported: high cholesterol EZETIMIBE NPC1L1 3.599016 Weighted median 0.97 8.725041e-28 0.329420 Tophits rs10260606 7 Coronary heart disease
433 Levulinate (4-oxovalerate) ISOXSUPRINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) TEDATIOXETINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) METARAMINOL ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) METHOXAMINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) TRIMIPRAMINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) MOXISYLYTE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) DIPIVEFRIN ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) PHENOXYBENZAMINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) ERGOLOID ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) MEPHENTERMINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) PHENTOLAMINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) PRAZOSIN ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) TOLAZOLINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) DAPIPRAZOLE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) ERGOTAMINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) OXYMETAZOLINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) PHENYLPROPANOLAMINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) DROXIDOPA ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) NAPHAZOLINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) MIDODRINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) LABETALOL ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) PHENYLEPHRINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) ALFUZOSIN ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) NOREPINEPHRINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) RAUWOLFIA SERPENTINA ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) TERAZOSIN ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) DOXAZOSIN ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) TETRAHYDROZOLINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) EPINEPHRINE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) SERTINDOLE ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) CARVEDILOL ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) TAMSULOSIN ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
433 Levulinate (4-oxovalerate) SILODOSIN ADRA1A -1.050062 FE IVW 1.00 7.509399e-27 0.097879 DF rs13278849 8 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease HMG COA REDUCTASE INHIBITORS LPA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs55730499 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease AMBRISENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease BOSENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease MACITENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease DARUSENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease ATRASENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease SPARSENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease CLAZOSENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease SITAXENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease ZIBOTENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease TEZOSENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease AVOSENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease NEBENTAN EDNRA 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs77249653 7 Coronary heart disease
UKB-a:534 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease ATORVASTATIN APOE 28.772442 Simple median 0.64 2.313367e-25 2.764826 Tophits rs429358 7 Coronary heart disease
UKB-a:203 Illnesses of father: None of the above (group 2) IMETELSTAT SODIUM TERT 1.092901 FE IVW 1.00 4.198756e-25 0.105598 DF rs2736098 7 Coronary heart disease
UKB-a:203 Illnesses of father: None of the above (group 2) IMETELSTAT TERT 1.092901 FE IVW 1.00 4.198756e-25 0.105598 DF rs2736098 7 Coronary heart disease
870 Concentration of IDL particles ATORVASTATIN APOE 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs7412 7 Coronary heart disease
870 Concentration of IDL particles ATORVASTATIN LDLR 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs137992968 7 Coronary heart disease
870 Concentration of IDL particles EVOLOCUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs11591147 7 Coronary heart disease
870 Concentration of IDL particles ALIROCUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs11591147 7 Coronary heart disease
870 Concentration of IDL particles BOCOCIZUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs11591147 7 Coronary heart disease
870 Concentration of IDL particles RALPANCIZUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs11591147 7 Coronary heart disease
870 Concentration of IDL particles EVOLOCUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs553741 7 Coronary heart disease
870 Concentration of IDL particles ALIROCUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs553741 7 Coronary heart disease
870 Concentration of IDL particles BOCOCIZUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs553741 7 Coronary heart disease
870 Concentration of IDL particles RALPANCIZUMAB PCSK9 0.323069 FE IVW 0.82 2.928658e-24 0.031792 HF rs553741 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above AMLODIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NIFEDIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NICARDIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above FELODIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CLEVIDIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NIMODIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above VERAPAMIL CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DILTIAZEM CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above SULOCTIDIL CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ISRADIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CINNARIZINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DRONEDARONE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above BEPRIDIL CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NISOLDIPINE CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above IMAGABALIN CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above AZD1305 CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ATAGABALIN CACNA1D -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs3821843 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above TOSEDOSTAT ENPEP -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs7670649 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above MIDOSTAURIN PRKD3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs13420463 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above UCN-01 PRKD3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs13420463 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above SOTRASTAURIN PRKD3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs13420463 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above GSK-690693 PRKD3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs13420463 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above SEVOFLURANE KCNK3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1275988 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ISOFLURANE KCNK3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1275988 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DESFLURANE KCNK3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1275988 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DOXAPRAM KCNK3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1275988 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above FULRANUMAB NGF -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs57748895 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above FASINUMAB NGF -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs57748895 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above TANEZUMAB NGF -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs57748895 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NESIRITIDE NPR1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs35479618 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above BEPRIDIL CACNB2 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12258967 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above SULOCTIDIL CACNB2 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12258967 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above IMAGABALIN CACNB2 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12258967 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ATAGABALIN CACNB2 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12258967 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above GEMCITABINE NT5C2 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs11191580 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above METOPROLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NOREPINEPHRINE ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above TIMOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NEBIVOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PROPRANOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above EPINEPHRINE ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CARVEDILOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above OXPRENOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ATENOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above BETAXOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above BISOPROLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CARTEOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DOBUTAMINE ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ACEBUTOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ESMOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above SOTALOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DOPAMINE ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PROPAFENONE ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above LABETALOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DROXIDOPA ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ISOPROTERENOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above NADOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CELIPROLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DIPIVEFRIN ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above METIPRANOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above MEPHENTERMINE ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above LEVOBUNOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PINDOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PENBUTOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above LEVOBETAXOLOL ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above LY377604 ADRB1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs1801253 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above RIOCIGUAT GUCY1A3 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs11724647 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above HMG COA REDUCTASE INHIBITORS LPA -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs56393506 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PBF-999 PDE10A -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs6932812 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DIPYRIDAMOLE PDE10A -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs6932812 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PENTOXIFYLLINE PDE10A -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs6932812 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN LISPRO INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN GLARGINE INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN DEGLUDEC INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN ASPART INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN DETEMIR INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN HUMAN INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN GLULISINE INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN PURIFIED PORK INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN SUSP ISOPHANE BEEF INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN PORK INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN SUSP ISOPHANE RECOMBINANT HUMAN INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN SUSP ISOPHANE SEMISYNTHETIC PURIFIED HUMAN INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN PURIFIED BEEF INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN LISPRO PROTAMINE RECOMBINANT INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN ASPART PROTAMINE RECOMBINANT INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN PEGLISPRO INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above LINSITINIB INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INSULIN ZINC SUSP RECOMBINANT HUMAN INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above BMS-754807 INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above KW-2450 INSR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs12985940 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ATORVASTATIN APOE -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs7412 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PEGINTERFERON ALFA-2B VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above RIBAVIRIN VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CALCIPOTRIENE VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CALCITRIOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ERGOCALCIFEROL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CHOLECALCIFEROL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PARICALCITOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DOXERCALCIFEROL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CALCIFEDIOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ALFACALCIDOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above SEOCALCITOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above PEFCALCITOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above DP001 VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above LUNACALCIPOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above INECALCITOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above BECOCALCIDIOL VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above ILX23-7553 VDR -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs117913411 7 Coronary heart disease
UKB-a:435 Vascular/heart problems diagnosed by doctor: None of the above CILASTATIN DPEP1 -1.638707 RE IVW 0.67 2.108854e-22 0.138587 DF rs164749 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin HMG COA REDUCTASE INHIBITORS HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin SIMVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ROSUVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin PRAVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin FLUVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin PITAVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin CERIVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin LOVASTATIN HMGCR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12916 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin EVOLOCUMAB PCSK9 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs11591147 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ALIROCUMAB PCSK9 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs11591147 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin BOCOCIZUMAB PCSK9 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs11591147 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin RALPANCIZUMAB PCSK9 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs11591147 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin SULFONAMIDES TCF7L2 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs12243326 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin HMG COA REDUCTASE INHIBITORS LPA 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs10455872 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN APOE 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs429358 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN LDLR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs2569550 7 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN LDLR 13.214148 Simple median 0.88 1.446911e-21 1.385326 Tophits rs8106503 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension BEPRIDIL CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs12258967 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SULOCTIDIL CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs12258967 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension IMAGABALIN CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs12258967 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ATAGABALIN CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs12258967 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension BEPRIDIL CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs11592100 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SULOCTIDIL CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs11592100 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension IMAGABALIN CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs11592100 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ATAGABALIN CACNB2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs11592100 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension IMETELSTAT SODIUM TERT 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7449190 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension IMETELSTAT TERT 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7449190 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension RIOCIGUAT GUCY1A3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs11724647 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension TOSEDOSTAT ENPEP 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs2881854 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN LISPRO INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN GLARGINE INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN DEGLUDEC INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN ASPART INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN DETEMIR INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN HUMAN INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN GLULISINE INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN PURIFIED PORK INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN SUSP ISOPHANE BEEF INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN PORK INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN SUSP ISOPHANE RECOMBINANT HUMAN INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN SUSP ISOPHANE SEMISYNTHETIC PURIFIED HUMAN INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN PURIFIED BEEF INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN LISPRO PROTAMINE RECOMBINANT INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN ASPART PROTAMINE RECOMBINANT INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN PEGLISPRO INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension LINSITINIB INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INSULIN ZINC SUSP RECOMBINANT HUMAN INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension BMS-754807 INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension KW-2450 INSR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7258382 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CAPTOPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension RAMIPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension FOSINOPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension BENAZEPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension LISINOPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension QUINAPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension TRANDOLAPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension PERINDOPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CAPTOPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ENALAPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CILAZAPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension MOEXIPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SPIRAPRIL ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ENALAPRILAT ACE 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs4968783 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CILASTATIN DPEP1 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs164749 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension PEGINTERFERON ALFA-2B VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension RIBAVIRIN VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CALCIPOTRIENE VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CALCITRIOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ERGOCALCIFEROL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CHOLECALCIFEROL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension PARICALCITOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DOXERCALCIFEROL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CALCIFEDIOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ALFACALCIDOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SEOCALCITOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension PEFCALCITOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DP001 VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension LUNACALCIPOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension INECALCITOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension BECOCALCIDIOL VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ILX23-7553 VDR 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs117913411 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension GEMCITABINE NT5C2 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs11191580 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension AMLODIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NIFEDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NICARDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension FELODIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CLEVIDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NIMODIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension VERAPAMIL CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DILTIAZEM CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SULOCTIDIL CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ISRADIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CINNARIZINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DRONEDARONE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension BEPRIDIL CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NISOLDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension IMAGABALIN CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension AZD1305 CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ATAGABALIN CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs3821843 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension AMLODIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NIFEDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NICARDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension FELODIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CLEVIDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NIMODIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension VERAPAMIL CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DILTIAZEM CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SULOCTIDIL CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ISRADIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension CINNARIZINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DRONEDARONE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension BEPRIDIL CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NISOLDIPINE CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension IMAGABALIN CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension AZD1305 CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ATAGABALIN CACNA1D 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs7340705 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SEVOFLURANE KCNK3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs1275988 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension ISOFLURANE KCNK3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs1275988 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DESFLURANE KCNK3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs1275988 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension DOXAPRAM KCNK3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs1275988 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension MIDOSTAURIN PRKD3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs13420463 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension UCN-01 PRKD3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs13420463 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension SOTRASTAURIN PRKD3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs13420463 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension GSK-690693 PRKD3 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs13420463 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension NESIRITIDE NPR1 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs35479618 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension FULRANUMAB NGF 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs57748895 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension FASINUMAB NGF 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs57748895 7 Coronary heart disease
UKB-a:61 Non-cancer illness code self-reported: hypertension TANEZUMAB NGF 1.555050 Simple median 0.90 4.693504e-21 0.165153 Tophits rs57748895 7 Coronary heart disease
781 LDL cholesterol HMG COA REDUCTASE INHIBITORS HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol SIMVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol ATORVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol ROSUVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol PRAVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol FLUVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol PITAVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol CERIVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol LOVASTATIN HMGCR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6453131 7 Coronary heart disease
781 LDL cholesterol EZETIMIBE NPC1L1 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs2073547 7 Coronary heart disease
781 LDL cholesterol EVOLOCUMAB PCSK9 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs11591147 7 Coronary heart disease
781 LDL cholesterol ALIROCUMAB PCSK9 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs11591147 7 Coronary heart disease
781 LDL cholesterol BOCOCIZUMAB PCSK9 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs11591147 7 Coronary heart disease
781 LDL cholesterol RALPANCIZUMAB PCSK9 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs11591147 7 Coronary heart disease
781 LDL cholesterol IRINOTECAN TOP1 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs2223745 7 Coronary heart disease
781 LDL cholesterol ETIRINOTECAN PEGOL TOP1 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs2223745 7 Coronary heart disease
781 LDL cholesterol IRINOTECAN SUCROSOFATE TOP1 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs2223745 7 Coronary heart disease
781 LDL cholesterol BECATECARIN TOP1 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs2223745 7 Coronary heart disease
781 LDL cholesterol ATORVASTATIN LDLR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs6511720 7 Coronary heart disease
781 LDL cholesterol ATORVASTATIN LDLR 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs2738447 7 Coronary heart disease
781 LDL cholesterol HMG COA REDUCTASE INHIBITORS CETP 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs183130 7 Coronary heart disease
781 LDL cholesterol DALCETRAPIB CETP 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs183130 7 Coronary heart disease
781 LDL cholesterol EVACETRAPIB CETP 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs183130 7 Coronary heart disease
781 LDL cholesterol ANACETRAPIB CETP 0.434779 Simple median 0.94 7.813840e-19 0.049057 HF rs183130 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication SEVOFLURANE KCNK3 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs1275986 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication ISOFLURANE KCNK3 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs1275986 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication DESFLURANE KCNK3 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs1275986 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication DOXAPRAM KCNK3 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs1275986 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication RIOCIGUAT GUCY1A3 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs2242296 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication FULRANUMAB NGF 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs57748895 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication FASINUMAB NGF 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs57748895 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication TANEZUMAB NGF 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs57748895 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication CILASTATIN DPEP1 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs908951 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication BEPRIDIL CACNB2 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs12258967 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication SULOCTIDIL CACNB2 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs12258967 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication IMAGABALIN CACNB2 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs12258967 7 Coronary heart disease
UKB-a:450 Medication for cholesterol blood pressure diabetes or take exogenous hormones: Blood pressure medication ATAGABALIN CACNB2 1.393856 FE IVW 0.90 1.361558e-18 0.158383 DF + HF rs12258967 7 Coronary heart disease
300 LDL cholesterol HMG COA REDUCTASE INHIBITORS HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol SIMVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol ATORVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol ROSUVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol PRAVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol FLUVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol PITAVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol CERIVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol LOVASTATIN HMGCR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs12916 7 Coronary heart disease
300 LDL cholesterol REGORAFENIB FRK 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6909746 7 Coronary heart disease
300 LDL cholesterol DASATINIB FRK 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6909746 7 Coronary heart disease
300 LDL cholesterol ILORASERTIB FRK 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6909746 7 Coronary heart disease
300 LDL cholesterol ENMD-981693 FRK 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6909746 7 Coronary heart disease
300 LDL cholesterol XL-228 FRK 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6909746 7 Coronary heart disease
300 LDL cholesterol EVOLOCUMAB PCSK9 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs11591147 7 Coronary heart disease
300 LDL cholesterol ALIROCUMAB PCSK9 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs11591147 7 Coronary heart disease
300 LDL cholesterol BOCOCIZUMAB PCSK9 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs11591147 7 Coronary heart disease
300 LDL cholesterol RALPANCIZUMAB PCSK9 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs11591147 7 Coronary heart disease
300 LDL cholesterol IRINOTECAN TOP1 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6065311 7 Coronary heart disease
300 LDL cholesterol ETIRINOTECAN PEGOL TOP1 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6065311 7 Coronary heart disease
300 LDL cholesterol IRINOTECAN SUCROSOFATE TOP1 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6065311 7 Coronary heart disease
300 LDL cholesterol BECATECARIN TOP1 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6065311 7 Coronary heart disease
300 LDL cholesterol ALVERINE HNF4A 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs1800961 7 Coronary heart disease
300 LDL cholesterol PROBUCOL ABCA1 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs1883025 7 Coronary heart disease
300 LDL cholesterol EZETIMIBE NPC1L1 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs2073547 7 Coronary heart disease
300 LDL cholesterol ATORVASTATIN LDLR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs6511720 7 Coronary heart disease
300 LDL cholesterol ATORVASTATIN LDLR 0.401022 Weighted median 0.98 7.558946e-18 0.046597 HF rs2738459 7 Coronary heart disease
908 Phospholipids in medium LDL ATORVASTATIN APOE 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs7412 7 Coronary heart disease
908 Phospholipids in medium LDL ATORVASTATIN LDLR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs79915079 7 Coronary heart disease
908 Phospholipids in medium LDL HMG COA REDUCTASE INHIBITORS HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL SIMVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL ATORVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL ROSUVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL PRAVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL FLUVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL PITAVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL CERIVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL LOVASTATIN HMGCR 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs12916 7 Coronary heart disease
908 Phospholipids in medium LDL EVOLOCUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs11591147 7 Coronary heart disease
908 Phospholipids in medium LDL ALIROCUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs11591147 7 Coronary heart disease
908 Phospholipids in medium LDL BOCOCIZUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs11591147 7 Coronary heart disease
908 Phospholipids in medium LDL RALPANCIZUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs11591147 7 Coronary heart disease
908 Phospholipids in medium LDL EVOLOCUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs2495477 7 Coronary heart disease
908 Phospholipids in medium LDL ALIROCUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs2495477 7 Coronary heart disease
908 Phospholipids in medium LDL BOCOCIZUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs2495477 7 Coronary heart disease
908 Phospholipids in medium LDL RALPANCIZUMAB PCSK9 0.374530 FE IVW 0.79 2.866399e-17 0.044313 HF rs2495477 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure TOSEDOSTAT ENPEP 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7670649 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure RIOCIGUAT GUCY1A3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs11724647 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure IMETELSTAT SODIUM TERT 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7449190 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure IMETELSTAT TERT 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7449190 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure FULRANUMAB NGF 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs57748895 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure FASINUMAB NGF 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs57748895 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure TANEZUMAB NGF 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs57748895 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NESIRITIDE NPR1 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs35479618 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure SEVOFLURANE KCNK3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs1275988 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ISOFLURANE KCNK3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs1275988 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DESFLURANE KCNK3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs1275988 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DOXAPRAM KCNK3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs1275988 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure MIDOSTAURIN PRKD3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs13420463 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure UCN-01 PRKD3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs13420463 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure SOTRASTAURIN PRKD3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs13420463 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure GSK-690693 PRKD3 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs13420463 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure AMLODIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NIFEDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NICARDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure FELODIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CLEVIDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NIMODIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure VERAPAMIL CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DILTIAZEM CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure SULOCTIDIL CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ISRADIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CINNARIZINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DRONEDARONE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure BEPRIDIL CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NISOLDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure IMAGABALIN CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure AZD1305 CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ATAGABALIN CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7340705 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure AMLODIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NIFEDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NICARDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure FELODIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CLEVIDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NIMODIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure VERAPAMIL CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DILTIAZEM CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure SULOCTIDIL CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ISRADIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CINNARIZINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DRONEDARONE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure BEPRIDIL CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure NISOLDIPINE CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure IMAGABALIN CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure AZD1305 CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ATAGABALIN CACNA1D 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs3821843 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure PEGINTERFERON ALFA-2B VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure RIBAVIRIN VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CALCIPOTRIENE VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CALCITRIOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ERGOCALCIFEROL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CHOLECALCIFEROL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure PARICALCITOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DOXERCALCIFEROL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CALCIFEDIOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ALFACALCIDOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure SEOCALCITOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure PEFCALCITOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure DP001 VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure LUNACALCIPOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INECALCITOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure BECOCALCIDIOL VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ILX23-7553 VDR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs117913411 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure BEPRIDIL CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7911644 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure SULOCTIDIL CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7911644 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure IMAGABALIN CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7911644 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ATAGABALIN CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7911644 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure GEMCITABINE NT5C2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs11191580 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure BEPRIDIL CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs12258967 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure SULOCTIDIL CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs12258967 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure IMAGABALIN CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs12258967 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure ATAGABALIN CACNB2 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs12258967 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure CILASTATIN DPEP1 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs164749 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN LISPRO INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN GLARGINE INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN DEGLUDEC INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN ASPART INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN DETEMIR INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN HUMAN INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN GLULISINE INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN PURIFIED PORK INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN SUSP ISOPHANE BEEF INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN PORK INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN SUSP ISOPHANE RECOMBINANT HUMAN INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN SUSP ISOPHANE SEMISYNTHETIC PURIFIED HUMAN INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN PURIFIED BEEF INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN LISPRO PROTAMINE RECOMBINANT INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN ASPART PROTAMINE RECOMBINANT INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN PEGLISPRO INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure LINSITINIB INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure INSULIN ZINC SUSP RECOMBINANT HUMAN INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure BMS-754807 INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:437 Vascular/heart problems diagnosed by doctor: High blood pressure KW-2450 INSR 1.362339 Weighted median 0.94 1.418714e-16 0.164869 HF rs7258382 7 Coronary heart disease
UKB-a:291 Trunk fat mass ATORVASTATIN APOE 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs429358 7 Coronary heart disease
UKB-a:291 Trunk fat mass OPICINUMAB LINGO1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11856579 7 Coronary heart disease
UKB-a:291 Trunk fat mass FIGITUMUMAB IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass MECASERMIN IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass LINSITINIB IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass TEPROTUMUMAB IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass CIXUTUMUMAB IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass DALOTUZUMAB IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass MECASERMIN RINFABATE IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass AXL-1717 IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass GANITUMAB IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass AVE-1642 IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass BMS-754807 IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass ROBATUMUMAB IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass KW-2450 IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass XL-228 IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass PL-225B IGF1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs6598540 7 Coronary heart disease
UKB-a:291 Trunk fat mass NARNATUMAB MST1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs9843653 7 Coronary heart disease
UKB-a:291 Trunk fat mass MK-8033 MST1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs9843653 7 Coronary heart disease
UKB-a:291 Trunk fat mass MGCD-265 MST1R 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs9843653 7 Coronary heart disease
UKB-a:291 Trunk fat mass MESALAMINE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass PIOGLITAZONE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass ROSIGLITAZONE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass BEZAFIBRATE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass TROGLITAZONE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass ALEGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass MURAGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass TESAGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass IMIGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass BARDOXOLONE METHYL PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass BALSALAZIDE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass RIVOGLITAZONE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass BALAGLITAZONE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass NAVEGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass INT131 PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass ARHALOFENATE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass SODELGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass OLSALAZINE PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass MK-0533 PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass MBX-2044 PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass FARGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass INDEGLITAZAR PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass DB959 PPARG 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs7649970 7 Coronary heart disease
UKB-a:291 Trunk fat mass TEGAFUR DPYD 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs75641275 7 Coronary heart disease
UKB-a:291 Trunk fat mass CAPECITABINE DPYD 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs75641275 7 Coronary heart disease
UKB-a:291 Trunk fat mass FLUOROURACIL DPYD 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs75641275 7 Coronary heart disease
UKB-a:291 Trunk fat mass ENILURACIL DPYD 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs75641275 7 Coronary heart disease
UKB-a:291 Trunk fat mass CRISABOROLE PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass ROFLUMILAST PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass DIPYRIDAMOLE PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass THEOPHYLLINE PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass APREMILAST PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass PENTOXIFYLLINE PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass DYPHYLLINE PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass AMLEXANOX PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass FLAVOXATE PDE4B 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs11208779 7 Coronary heart disease
UKB-a:291 Trunk fat mass PALBOCICLIB CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass RIBOCICLIB CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass ABEMACICLIB CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass RONICICLIB CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass ALVOCIDIB CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass UCN-01 CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass AT-7519 CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass PHA-793887 CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass AZD-5438 CDK6 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs10269774 7 Coronary heart disease
UKB-a:291 Trunk fat mass RAD1901 ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass FISPEMIFENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ACOLBIFENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ESTROGENS, ESTERIFIED ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ESTRONE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass BRILANESTRANT ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass AFIMOXIFENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass GTX-758 ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass SR16234 ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass SYNTHETIC CONJUGATED ESTROGENS, B ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ARZOXIFENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass DIETHYLSTILBESTROL DIPHOSPHATE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass POLYESTRADIOL PHOSPHATE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass BAZEDOXIFENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass DIETHYLSTILBESTROL ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass OSPEMIFENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass TOREMIFENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass FULVESTRANT ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass TAMOXIFEN ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ETHINYL ESTRADIOL ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ESTRADIOL VALERATE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass CLOMIPHENE ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ESTROGENS, CONJUGATED ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:291 Trunk fat mass ESTRADIOL ESR1 0.255400 FE IVW 0.82 6.364277e-16 0.031601 DF rs3853252 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication CAPTOPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication RAMIPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication FOSINOPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication BENAZEPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication LISINOPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication QUINAPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication TRANDOLAPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication PERINDOPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication CAPTOPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication ENALAPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication CILAZAPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication MOEXIPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication SPIRAPRIL ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication ENALAPRILAT ACE 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1800764 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication BEPRIDIL CACNB2 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs7070847 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication SULOCTIDIL CACNB2 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs7070847 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication IMAGABALIN CACNB2 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs7070847 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication ATAGABALIN CACNB2 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs7070847 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication SEVOFLURANE KCNK3 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1275984 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication ISOFLURANE KCNK3 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1275984 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication DESFLURANE KCNK3 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1275984 7 Coronary heart disease
UKB-a:490 Medication for cholesterol blood pressure or diabetes: Blood pressure medication DOXAPRAM KCNK3 1.202727 FE IVW 0.91 8.089278e-16 0.149354 HF rs1275984 7 Coronary heart disease
908 Phospholipids in medium LDL ATORVASTATIN APOE 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs7412 6 Coronary heart disease
908 Phospholipids in medium LDL ATORVASTATIN LDLR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs79915079 6 Coronary heart disease
908 Phospholipids in medium LDL HMG COA REDUCTASE INHIBITORS HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL SIMVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL ATORVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL ROSUVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL PRAVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL FLUVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL PITAVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL CERIVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL LOVASTATIN HMGCR 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs12916 6 Coronary heart disease
908 Phospholipids in medium LDL EVOLOCUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs11591147 6 Coronary heart disease
908 Phospholipids in medium LDL ALIROCUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs11591147 6 Coronary heart disease
908 Phospholipids in medium LDL BOCOCIZUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs11591147 6 Coronary heart disease
908 Phospholipids in medium LDL RALPANCIZUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs11591147 6 Coronary heart disease
908 Phospholipids in medium LDL EVOLOCUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs2495477 6 Coronary heart disease
908 Phospholipids in medium LDL ALIROCUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs2495477 6 Coronary heart disease
908 Phospholipids in medium LDL BOCOCIZUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs2495477 6 Coronary heart disease
908 Phospholipids in medium LDL RALPANCIZUMAB PCSK9 0.576435 FE IVW 1.00 8.902493e-16 0.071686 DF rs2495477 6 Coronary heart disease
859 Glucose TASIMELTEON MTNR1B 0.090048 FE IVW 1.00 2.052121e-15 0.011344 DF rs10466351 6 Coronary heart disease
859 Glucose AGOMELATINE MTNR1B 0.090048 FE IVW 1.00 2.052121e-15 0.011344 DF rs10466351 6 Coronary heart disease
859 Glucose RAMELTEON MTNR1B 0.090048 FE IVW 1.00 2.052121e-15 0.011344 DF rs10466351 6 Coronary heart disease
301 Total cholesterol ATORVASTATIN LDLR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs6511720 7 Coronary heart disease
301 Total cholesterol ATORVASTATIN LDLR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs2738459 7 Coronary heart disease
301 Total cholesterol ATORVASTATIN APOE 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs7412 7 Coronary heart disease
301 Total cholesterol HMG COA REDUCTASE INHIBITORS HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol SIMVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol ATORVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol ROSUVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol PRAVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol FLUVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol PITAVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol CERIVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol LOVASTATIN HMGCR 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs12916 7 Coronary heart disease
301 Total cholesterol REGORAFENIB FRK 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11153594 7 Coronary heart disease
301 Total cholesterol DASATINIB FRK 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11153594 7 Coronary heart disease
301 Total cholesterol ILORASERTIB FRK 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11153594 7 Coronary heart disease
301 Total cholesterol ENMD-981693 FRK 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11153594 7 Coronary heart disease
301 Total cholesterol XL-228 FRK 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11153594 7 Coronary heart disease
301 Total cholesterol EZETIMIBE NPC1L1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs2073547 7 Coronary heart disease
301 Total cholesterol PROBUCOL ABCA1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs1883025 7 Coronary heart disease
301 Total cholesterol PROBUCOL ABCA1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11789603 7 Coronary heart disease
301 Total cholesterol FENOFIBRATE PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol GEMFIBROZIL PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol FENOFIBRIC ACID PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol CLOFIBRATE PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol BEZAFIBRATE PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol CIPROFIBRATE PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol ALEGLITAZAR PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol IMIGLITAZAR PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol TESAGLITAZAR PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol K-877 PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol MURAGLITAZAR PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol LY-518674 PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol GW590735 PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol INDEGLITAZAR PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol ZYH7 PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol NAVEGLITAZAR PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol SODELGLITAZAR PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol CP-778875 PPARA 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs4253772 7 Coronary heart disease
301 Total cholesterol ALVERINE HNF4A 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs1800961 7 Coronary heart disease
301 Total cholesterol EVOLOCUMAB PCSK9 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11591147 7 Coronary heart disease
301 Total cholesterol ALIROCUMAB PCSK9 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11591147 7 Coronary heart disease
301 Total cholesterol BOCOCIZUMAB PCSK9 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11591147 7 Coronary heart disease
301 Total cholesterol RALPANCIZUMAB PCSK9 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11591147 7 Coronary heart disease
301 Total cholesterol BELINOSTAT UGT1A1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11563251 7 Coronary heart disease
301 Total cholesterol IRINOTECAN UGT1A1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11563251 7 Coronary heart disease
301 Total cholesterol ATAZANAVIR UGT1A1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11563251 7 Coronary heart disease
301 Total cholesterol PAZOPANIB UGT1A1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11563251 7 Coronary heart disease
301 Total cholesterol NILOTINIB UGT1A1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11563251 7 Coronary heart disease
301 Total cholesterol DOLUTEGRAVIR UGT1A1 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11563251 7 Coronary heart disease
301 Total cholesterol LAMOTRIGINE UGT1A4 0.381323 Simple median 0.93 8.390057e-15 0.049130 Tophits rs11563251 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading OMECAMTIV MECARBIL MYH6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs365990 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading TRIAMCINOLONE CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading FLUTICASONE/SALMETEROL CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading FLUTICASONE PROPIONATE CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading BUDESONIDE CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ONO-2333MS CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading SSR125543 CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading PEXACERFONT CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading VERUCERFONT CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading EMICERFONT CRHR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs55938136 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ATACICEPT TNFSF13 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs78744936 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading LY2940094 OPRL1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs8121509 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading CEBRANOPADOL OPRL1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs8121509 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading FINGOLIMOD S1PR2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10409243 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading AMISELIMOD S1PR2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10409243 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading DECITABINE DNMT1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10409243 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading AZACITIDINE DNMT1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10409243 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading PALBOCICLIB CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading RIBOCICLIB CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ABEMACICLIB CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading RONICICLIB CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ALVOCIDIB CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading UCN-01 CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading AT-7519 CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading PHA-793887 CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading AZD-5438 CDK6 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs10269774 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading GEMCITABINE NT5C2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs11191580 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading BEPRIDIL CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs12258967 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading SULOCTIDIL CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs12258967 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading IMAGABALIN CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs12258967 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ATAGABALIN CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs12258967 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading BEPRIDIL CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1779240 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading SULOCTIDIL CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1779240 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading IMAGABALIN CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1779240 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ATAGABALIN CACNB2 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1779240 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading LORVOTUZUMAB MERTANSINE NCAM1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs11214436 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading BB-10901 NCAM1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs11214436 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading FOMEPIZOLE ADH1B 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1229984 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading L19IL2 FN1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1250259 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading OCRIPLASMIN FN1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1250259 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading L19TNFA FN1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1250259 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading L19SIP 131I FN1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1250259 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading CARGLUMIC ACID CPS1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1047891 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading VALPROIC ACID CPS1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs1047891 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading AMLODIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading NIFEDIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading NICARDIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading FELODIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading CLEVIDIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading NIMODIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading VERAPAMIL CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading DILTIAZEM CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading SULOCTIDIL CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ISRADIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading CINNARIZINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading DRONEDARONE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading BEPRIDIL CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading NISOLDIPINE CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading IMAGABALIN CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading AZD1305 CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ATAGABALIN CACNA1D 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35593046 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading NESIRITIDE NPR1 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35479618 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading SEVOFLURANE KCNK3 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35021474 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading ISOFLURANE KCNK3 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35021474 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading DESFLURANE KCNK3 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35021474 7 Coronary heart disease
UKB-a:360 Systolic blood pressure automated reading DOXAPRAM KCNK3 0.592952 Simple median 0.93 1.017830e-14 0.076638 HF rs35021474 7 Coronary heart disease
300 LDL cholesterol HMG COA REDUCTASE INHIBITORS HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol SIMVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol ATORVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol ROSUVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol PRAVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol FLUVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol PITAVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol CERIVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol LOVASTATIN HMGCR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs12916 8 Coronary heart disease
300 LDL cholesterol REGORAFENIB FRK 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6909746 8 Coronary heart disease
300 LDL cholesterol DASATINIB FRK 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6909746 8 Coronary heart disease
300 LDL cholesterol ILORASERTIB FRK 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6909746 8 Coronary heart disease
300 LDL cholesterol ENMD-981693 FRK 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6909746 8 Coronary heart disease
300 LDL cholesterol XL-228 FRK 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6909746 8 Coronary heart disease
300 LDL cholesterol EVOLOCUMAB PCSK9 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs11591147 8 Coronary heart disease
300 LDL cholesterol ALIROCUMAB PCSK9 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs11591147 8 Coronary heart disease
300 LDL cholesterol BOCOCIZUMAB PCSK9 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs11591147 8 Coronary heart disease
300 LDL cholesterol RALPANCIZUMAB PCSK9 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs11591147 8 Coronary heart disease
300 LDL cholesterol IRINOTECAN TOP1 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6065311 8 Coronary heart disease
300 LDL cholesterol ETIRINOTECAN PEGOL TOP1 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6065311 8 Coronary heart disease
300 LDL cholesterol IRINOTECAN SUCROSOFATE TOP1 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6065311 8 Coronary heart disease
300 LDL cholesterol BECATECARIN TOP1 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6065311 8 Coronary heart disease
300 LDL cholesterol ALVERINE HNF4A 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs1800961 8 Coronary heart disease
300 LDL cholesterol PROBUCOL ABCA1 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs1883025 8 Coronary heart disease
300 LDL cholesterol EZETIMIBE NPC1L1 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs2073547 8 Coronary heart disease
300 LDL cholesterol ATORVASTATIN LDLR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs6511720 8 Coronary heart disease
300 LDL cholesterol ATORVASTATIN LDLR 0.429429 RE IVW 0.89 1.871557e-14 0.043389 HF rs2738459 8 Coronary heart disease
UKB-a:283 Arm fat mass (right) ATORVASTATIN APOE 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs429358 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FIGITUMUMAB IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MECASERMIN IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) LINSITINIB IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TEPROTUMUMAB IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) CIXUTUMUMAB IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DALOTUZUMAB IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MECASERMIN RINFABATE IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AXL-1717 IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) GANITUMAB IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AVE-1642 IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BMS-754807 IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ROBATUMUMAB IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) KW-2450 IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) XL-228 IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PL-225B IGF1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs56803094 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) OSIMERTINIB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NERATINIB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) VANDETANIB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DACOMITINIB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PATRITUMAB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MM-121 ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) POZIOTINIB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) SERIBANTUMAB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DULIGOTUZUMAB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) LUMRETUZUMAB ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AMG-888 ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AV-203 ERBB3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs2292238 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TRAMADOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ALFENTANIL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FENTANYL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ETHANOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALTREXONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALOXONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MORPHINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) METHADONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AXOMADOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ODELEPRAN OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FENTANYL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) HYDROMORPHONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) OXYCODONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) CODEINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) HYDROCODONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TRAMADOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MORPHINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALTREXONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALOXONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) LOPERAMIDE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BUPRENORPHINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) REMIFENTANIL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) METHADONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) SUFENTANIL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) OXYMORPHONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TAPENTADOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) LEVOMETHADYL ACETATE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DIHYDROCODEINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MEPERIDINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DEZOCINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) METHYLNALTREXONE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALOXEGOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ELUXADOLINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PROPOXYPHENE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DEXTROMORAMIDE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALBUPHINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ALFENTANIL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BUTORPHANOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ALVIMOPAN OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALMEFENE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NALDEMEDINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) OLICERIDINE OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) METHYLSAMIDORPHAN OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FAXELADOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) SAMIDORPHAN OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AXELOPRAN OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) CEBRANOPADOL OPRM1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9688977 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BENSERAZIDE DDC 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs1470749 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) CARBIDOPA DDC 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs1470749 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DOFETILIDE KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) SOTALOL KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DALFAMPRIDINE KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AMIODARONE KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TEDISAMIL KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) IBUTILIDE KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AZD1305 KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AZD7009 KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NERISPIRDINE KCNH2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10236214 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PALBOCICLIB CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) RIBOCICLIB CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ABEMACICLIB CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) RONICICLIB CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ALVOCIDIB CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) UCN-01 CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AT-7519 CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PHA-793887 CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AZD-5438 CDK6 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs10269774 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NERISPIRDINE KCNB2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7845090 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DALFAMPRIDINE KCNB2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7845090 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TEDISAMIL KCNB2 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7845090 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MESALAMINE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PIOGLITAZONE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ROSIGLITAZONE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BEZAFIBRATE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TROGLITAZONE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ALEGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MURAGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TESAGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) IMIGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BARDOXOLONE METHYL PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BALSALAZIDE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) RIVOGLITAZONE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BALAGLITAZONE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NAVEGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) INT131 PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ARHALOFENATE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) SODELGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) OLSALAZINE PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MK-0533 PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MBX-2044 PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FARGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) INDEGLITAZAR PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DB959 PPARG 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs7649970 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NARNATUMAB MST1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9843653 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MK-8033 MST1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9843653 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MGCD-265 MST1R 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs9843653 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TEZAMPANEL GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PF-04958242 GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) SELURAMPANEL GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MIBAMPATOR GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FARAMPATOR GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ZONAMPANEL GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) MK-8777 GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PERAMPANEL GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TOPIRAMATE GRIA1 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4502882 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AT-7519 CDK11B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs79113395 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) RONICICLIB CDK11B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs79113395 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PHA-793887 CDK11B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs79113395 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AZD-5438 CDK11B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs79113395 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) TEGAFUR DPYD 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs12072739 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) CAPECITABINE DPYD 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs12072739 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FLUOROURACIL DPYD 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs12072739 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ENILURACIL DPYD 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs12072739 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) LEVETIRACETAM SV2A 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11205277 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BRIVARACETAM SV2A 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11205277 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) CRISABOROLE PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ROFLUMILAST PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DIPYRIDAMOLE PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) THEOPHYLLINE PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) APREMILAST PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) PENTOXIFYLLINE PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DYPHYLLINE PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AMLEXANOX PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) FLAVOXATE PDE4B 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs11208779 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) SEVOFLURANE KCNK3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs935166 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) ISOFLURANE KCNK3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs935166 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DESFLURANE KCNK3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs935166 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DOXAPRAM KCNK3 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs935166 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) JNJ-26483327 ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AC-480 ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) CANERTINIB ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) BMS-690514 ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) POZIOTINIB ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) DACOMITINIB ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) OSIMERTINIB ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) VANDETANIB ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) NERATINIB ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
UKB-a:283 Arm fat mass (right) AFATINIB ERBB4 0.405549 Simple median 0.84 2.898637e-14 0.053342 HF rs4673617 7 Coronary heart disease
782 Total cholesterol EVOLOCUMAB PCSK9 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs11591147 7 Coronary heart disease
782 Total cholesterol ALIROCUMAB PCSK9 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs11591147 7 Coronary heart disease
782 Total cholesterol BOCOCIZUMAB PCSK9 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs11591147 7 Coronary heart disease
782 Total cholesterol RALPANCIZUMAB PCSK9 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs11591147 7 Coronary heart disease
782 Total cholesterol ATORVASTATIN APOE 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs7412 7 Coronary heart disease
782 Total cholesterol ATORVASTATIN LDLR 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs6511720 7 Coronary heart disease
782 Total cholesterol ATORVASTATIN LDLR 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs2738447 7 Coronary heart disease
782 Total cholesterol HMG COA REDUCTASE INHIBITORS CETP 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs183130 7 Coronary heart disease
782 Total cholesterol DALCETRAPIB CETP 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs183130 7 Coronary heart disease
782 Total cholesterol EVACETRAPIB CETP 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs183130 7 Coronary heart disease
782 Total cholesterol ANACETRAPIB CETP 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs183130 7 Coronary heart disease
782 Total cholesterol PROBUCOL ABCA1 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs2575876 7 Coronary heart disease
782 Total cholesterol EZETIMIBE NPC1L1 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs2073547 7 Coronary heart disease
782 Total cholesterol ALVERINE HNF4A 0.416497 RE IVW 0.91 3.191500e-14 0.032879 HF rs1800961 7 Coronary heart disease
885 Phospholipids in large LDL ATORVASTATIN LDLR 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs79915079 7 Coronary heart disease
885 Phospholipids in large LDL ATORVASTATIN APOE 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs7412 7 Coronary heart disease
885 Phospholipids in large LDL EVOLOCUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs553741 7 Coronary heart disease
885 Phospholipids in large LDL ALIROCUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs553741 7 Coronary heart disease
885 Phospholipids in large LDL BOCOCIZUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs553741 7 Coronary heart disease
885 Phospholipids in large LDL RALPANCIZUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs553741 7 Coronary heart disease
885 Phospholipids in large LDL EVOLOCUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs11591147 7 Coronary heart disease
885 Phospholipids in large LDL ALIROCUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs11591147 7 Coronary heart disease
885 Phospholipids in large LDL BOCOCIZUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs11591147 7 Coronary heart disease
885 Phospholipids in large LDL RALPANCIZUMAB PCSK9 0.405731 Weighted median 0.82 5.815459e-14 0.054010 HF rs11591147 7 Coronary heart disease
933 Serum total cholesterol EVOLOCUMAB PCSK9 0.332426 Penalised median 0.81 6.550571e-14 0.044344 DF rs11591147 7 Coronary heart disease
933 Serum total cholesterol ALIROCUMAB PCSK9 0.332426 Penalised median 0.81 6.550571e-14 0.044344 DF rs11591147 7 Coronary heart disease
933 Serum total cholesterol BOCOCIZUMAB PCSK9 0.332426 Penalised median 0.81 6.550571e-14 0.044344 DF rs11591147 7 Coronary heart disease
933 Serum total cholesterol RALPANCIZUMAB PCSK9 0.332426 Penalised median 0.81 6.550571e-14 0.044344 DF rs11591147 7 Coronary heart disease
933 Serum total cholesterol ATORVASTATIN APOE 0.332426 Penalised median 0.81 6.550571e-14 0.044344 DF rs7412 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CRISABOROLE PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ROFLUMILAST PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DIPYRIDAMOLE PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) THEOPHYLLINE PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) APREMILAST PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PENTOXIFYLLINE PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DYPHYLLINE PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AMLEXANOX PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) FLAVOXATE PDE4B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11208779 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AT-7519 CDK11B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs79113395 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) RONICICLIB CDK11B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs79113395 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PHA-793887 CDK11B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs79113395 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AZD-5438 CDK11B 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs79113395 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TEZAMPANEL GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PF-04958242 GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) SELURAMPANEL GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MIBAMPATOR GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) FARAMPATOR GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ZONAMPANEL GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MK-8777 GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PERAMPANEL GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TOPIRAMATE GRIA1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs4502882 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TRAMADOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ALFENTANIL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) FENTANYL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ETHANOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALTREXONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALOXONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MORPHINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) METHADONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AXOMADOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ODELEPRAN OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) FENTANYL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) HYDROMORPHONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) OXYCODONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CODEINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) HYDROCODONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TRAMADOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MORPHINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALTREXONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALOXONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) LOPERAMIDE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) BUPRENORPHINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) REMIFENTANIL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) METHADONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) SUFENTANIL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) OXYMORPHONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TAPENTADOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) LEVOMETHADYL ACETATE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DIHYDROCODEINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MEPERIDINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DEZOCINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) METHYLNALTREXONE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALOXEGOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ELUXADOLINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PROPOXYPHENE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DEXTROMORAMIDE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALBUPHINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ALFENTANIL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) BUTORPHANOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ALVIMOPAN OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALMEFENE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NALDEMEDINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) OLICERIDINE OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) METHYLSAMIDORPHAN OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) FAXELADOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) SAMIDORPHAN OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AXELOPRAN OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CEBRANOPADOL OPRM1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9688977 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ABITUZUMAB ITGB6 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs10803762 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) INTETUMUMAB ITGB6 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs10803762 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) STX-100 ITGB6 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs10803762 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) OXCARBAZEPINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PRILOCAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) LIDOCAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) RUFINAMIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) LAMOTRIGINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ROPIVACAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ZONISAMIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TOPIRAMATE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MEPIVACAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CARBAMAZEPINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ERLOSAMIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PHENYTOIN SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) QUINIDINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PROPAFENONE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DRONEDARONE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ESLICARBAZEPINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ARTICAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CHLOROPROCAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TETRACAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) RILUZOLE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MORICIZINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) QUINIDINE POLYGALACTURONATE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) FOSPHENYTOIN SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MEXILETINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PHENACEMIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DISOPYRAMIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ORPHENADRINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TOCAINIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ENCAINIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ESLICARBAZEPINE ACETATE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MEPHENYTOIN SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) BENOXINATE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PRIMIDONE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ETHOTOIN SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PROCAINAMIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PHENAZOPYRIDINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PROPARACAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) RALFINAMIDE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NW-3509 SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NERISPIRDINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PROCAINE SCN2A 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs12477385 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) SEVOFLURANE KCNK3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs935166 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ISOFLURANE KCNK3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs935166 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DESFLURANE KCNK3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs935166 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DOXAPRAM KCNK3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs935166 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NARNATUMAB MST1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9843653 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MK-8033 MST1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9843653 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MGCD-265 MST1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs9843653 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) JNJ-26483327 ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AC-480 ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CANERTINIB ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) BMS-690514 ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) POZIOTINIB ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DACOMITINIB ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) OSIMERTINIB ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) VANDETANIB ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NERATINIB ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AFATINIB ERBB4 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs16846140 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) OPICINUMAB LINGO1 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs11856579 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) FIGITUMUMAB IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MECASERMIN IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) LINSITINIB IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TEPROTUMUMAB IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CIXUTUMUMAB IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DALOTUZUMAB IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MECASERMIN RINFABATE IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AXL-1717 IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) GANITUMAB IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AVE-1642 IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) BMS-754807 IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ROBATUMUMAB IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) KW-2450 IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) XL-228 IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PL-225B IGF1R 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs56803094 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ANTHRACYCLINES AND RELATED SUBSTANCES HAS3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs7189149 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) OSIMERTINIB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NERATINIB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) VANDETANIB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DACOMITINIB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) PATRITUMAB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MM-121 ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) POZIOTINIB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) SERIBANTUMAB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DULIGOTUZUMAB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) LUMRETUZUMAB ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AMG-888 ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AV-203 ERBB3 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs2292238 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DOFETILIDE KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) SOTALOL KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) DALFAMPRIDINE KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AMIODARONE KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) TEDISAMIL KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) IBUTILIDE KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AZD1305 KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) AZD7009 KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) NERISPIRDINE KCNH2 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs1805123 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) ROCURONIUM CHRNE 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs7774 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) CISATRACURIUM CHRNE 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs7774 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) VECURONIUM CHRNE 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs7774 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) SUXAMETHONIUM CHRNE 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs7774 7 Coronary heart disease
UKB-a:248 Body mass index (BMI) MIVACURIUM CHRNE 0.353634 Simple median 0.80 9.473961e-14 0.047480 HF rs7774 7 Coronary heart disease
UKB-a:195 Sitting height SIMTUZUMAB LOXL2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs13271505 7 Coronary heart disease
UKB-a:195 Sitting height TREBANANIB ANGPT2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs76020419 7 Coronary heart disease
UKB-a:195 Sitting height NESVACUMAB ANGPT2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs76020419 7 Coronary heart disease
UKB-a:195 Sitting height VANUCIZUMAB ANGPT2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs76020419 7 Coronary heart disease
UKB-a:195 Sitting height PALBOCICLIB CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height RIBOCICLIB CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height ABEMACICLIB CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height RONICICLIB CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height ALVOCIDIB CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height UCN-01 CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height AT-7519 CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height PHA-793887 CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height AZD-5438 CDK6 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs42044 7 Coronary heart disease
UKB-a:195 Sitting height COBICISTAT CYP3A7 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs45446698 7 Coronary heart disease
UKB-a:195 Sitting height ROMIDEPSIN HDAC9 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1178166 7 Coronary heart disease
UKB-a:195 Sitting height PANOBINOSTAT HDAC9 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1178166 7 Coronary heart disease
UKB-a:195 Sitting height BELINOSTAT HDAC9 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1178166 7 Coronary heart disease
UKB-a:195 Sitting height TACEDINALINE HDAC9 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1178166 7 Coronary heart disease
UKB-a:195 Sitting height ENTINOSTAT HDAC9 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1178166 7 Coronary heart disease
UKB-a:195 Sitting height FIMEPINOSTAT HDAC9 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1178166 7 Coronary heart disease
UKB-a:195 Sitting height CUDC-101 HDAC9 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1178166 7 Coronary heart disease
UKB-a:195 Sitting height RAD1901 ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height FISPEMIFENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ACOLBIFENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ESTROGENS, ESTERIFIED ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ESTRONE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height BRILANESTRANT ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height AFIMOXIFENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height GTX-758 ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height SR16234 ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height SYNTHETIC CONJUGATED ESTROGENS, B ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ARZOXIFENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height DIETHYLSTILBESTROL DIPHOSPHATE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height POLYESTRADIOL PHOSPHATE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height BAZEDOXIFENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height DIETHYLSTILBESTROL ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height OSPEMIFENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height TOREMIFENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height FULVESTRANT ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height TAMOXIFEN ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ETHINYL ESTRADIOL ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ESTRADIOL VALERATE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height CLOMIPHENE ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ESTROGENS, CONJUGATED ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height ESTRADIOL ESR1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3853252 7 Coronary heart disease
UKB-a:195 Sitting height OCRIPLASMIN LAMA2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs7754167 7 Coronary heart disease
UKB-a:195 Sitting height OXCARBAZEPINE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height PHENYTOIN HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height CARBAMAZEPINE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height ABACAVIR HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height ALLOPURINOL HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height DAPSONE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height CARBIMAZOLE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height NEVIRAPINE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height PROPYLTHIOURACIL HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height METHIMAZOLE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height METHAZOLAMIDE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height OXCARBAZEPINE HLA-B -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2523578 7 Coronary heart disease
UKB-a:195 Sitting height COPANLISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height BUPARLISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height TASELISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height GEDATOLISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height DACTOLISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height PF-04691502 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height PICTILISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height SONOLISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height APITOLISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height SF-1126 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height RG-7666 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height LY-3023414 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height PILARALISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height VOXTALISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height OMIPALISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height VS-5584 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height PANULISIB PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height PA-799 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height DS-7423 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height BGT-226 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height ZSTK-474 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height WX-037 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height GSK-1059615 PIK3R1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs3756668 7 Coronary heart disease
UKB-a:195 Sitting height E-6201 MAP3K1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs832552 7 Coronary heart disease
UKB-a:195 Sitting height CC-401 MAPK10 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs7681267 7 Coronary heart disease
UKB-a:195 Sitting height TANZISERTIB MAPK10 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs7681267 7 Coronary heart disease
UKB-a:195 Sitting height MACIMORELIN GHSR -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs519384 7 Coronary heart disease
UKB-a:195 Sitting height ANAMORELIN GHSR -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs519384 7 Coronary heart disease
UKB-a:195 Sitting height IBUTAMOREN GHSR -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs519384 7 Coronary heart disease
UKB-a:195 Sitting height ULIMORELIN GHSR -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs519384 7 Coronary heart disease
UKB-a:195 Sitting height AZD-6738 ATR -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs11719737 7 Coronary heart disease
UKB-a:195 Sitting height BERZOSERTIB ATR -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs11719737 7 Coronary heart disease
UKB-a:195 Sitting height COLLAGENASE CLOSTRIDIUM HISTOLYTICUM COL5A2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs78905646 7 Coronary heart disease
UKB-a:195 Sitting height OCRIPLASMIN COL5A2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs78905646 7 Coronary heart disease
UKB-a:195 Sitting height OPROZOMIB PSMD4 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs35485741 7 Coronary heart disease
UKB-a:195 Sitting height IPATASERTIB AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height AZD-5363 AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height UPROSERTIB AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height MK-2206 AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height AFURESERTIB AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height TRICIRIBINE PHOSPHATE AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height MSC-2363318A AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height LY-2780301 AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height ARQ-092 AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height GSK-690693 AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height XL-418 AKT3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12134270 7 Coronary heart disease
UKB-a:195 Sitting height FRESOLIMUMAB TGFB2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2798631 7 Coronary heart disease
UKB-a:195 Sitting height COPANLISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height TASELISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height BUPARLISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height PICTILISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height RG-7666 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height GEDATOLISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height DACTOLISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height SF-1126 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height APITOLISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height PILARALISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height LY-3023414 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height SONOLISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height PF-04691502 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height ZSTK-474 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height BGT-226 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height VOXTALISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height GSK-1059615 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height PA-799 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height DS-7423 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height OMIPALISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height PANULISIB PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height VS-5584 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height WX-037 PIK3R3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1768809 7 Coronary heart disease
UKB-a:195 Sitting height OCRIPLASMIN COL11A1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12722976 7 Coronary heart disease
UKB-a:195 Sitting height COLLAGENASE CLOSTRIDIUM HISTOLYTICUM COL11A1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12722976 7 Coronary heart disease
UKB-a:195 Sitting height MIDOSTAURIN PRKCZ -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12082939 7 Coronary heart disease
UKB-a:195 Sitting height UCN-01 PRKCZ -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12082939 7 Coronary heart disease
UKB-a:195 Sitting height SOTRASTAURIN PRKCZ -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12082939 7 Coronary heart disease
UKB-a:195 Sitting height GSK-690693 PRKCZ -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12082939 7 Coronary heart disease
UKB-a:195 Sitting height COLLAGENASE CLOSTRIDIUM HISTOLYTICUM COL6A2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1043801 7 Coronary heart disease
UKB-a:195 Sitting height OCRIPLASMIN COL6A2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1043801 7 Coronary heart disease
UKB-a:195 Sitting height BUPIVACAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height RILUZOLE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height TOPIRAMATE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height LAMOTRIGINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ROPIVACAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height LIDOCAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height OXCARBAZEPINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height RANOLAZINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height DRONEDARONE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height MEPIVACAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PRILOCAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ZONISAMIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height CARBAMAZEPINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PHENYTOIN SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height LEVOBUPIVACAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ARTICAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PROPAFENONE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ERLOSAMIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height RUFINAMIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height TETRACAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PRIMIDONE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height QUINIDINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PROCAINAMIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height CHLOROPROCAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height MEPHENYTOIN SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height MORICIZINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height DISOPYRAMIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ORPHENADRINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ESLICARBAZEPINE ACETATE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height FOSPHENYTOIN SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height QUINIDINE POLYGALACTURONATE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ETHOTOIN SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height TOCAINIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height MEXILETINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ESLICARBAZEPINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PHENAZOPYRIDINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ENCAINIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height BENOXINATE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PHENACEMIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PROPARACAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height RALFINAMIDE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height NW-3509 SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height NERISPIRDINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height PROCAINE SCN4A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2532111 7 Coronary heart disease
UKB-a:195 Sitting height ROMIDEPSIN HDAC5 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs113886615 7 Coronary heart disease
UKB-a:195 Sitting height PANOBINOSTAT HDAC5 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs113886615 7 Coronary heart disease
UKB-a:195 Sitting height BELINOSTAT HDAC5 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs113886615 7 Coronary heart disease
UKB-a:195 Sitting height ENTINOSTAT HDAC5 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs113886615 7 Coronary heart disease
UKB-a:195 Sitting height TACEDINALINE HDAC5 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs113886615 7 Coronary heart disease
UKB-a:195 Sitting height FIMEPINOSTAT HDAC5 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs113886615 7 Coronary heart disease
UKB-a:195 Sitting height CUDC-101 HDAC5 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs113886615 7 Coronary heart disease
UKB-a:195 Sitting height LONAFARNIB FNTB -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2296316 7 Coronary heart disease
UKB-a:195 Sitting height TIPIFARNIB FNTB -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2296316 7 Coronary heart disease
UKB-a:195 Sitting height AMINOGLUTETHIMIDE CYP19A1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12900487 7 Coronary heart disease
UKB-a:195 Sitting height EXEMESTANE CYP19A1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12900487 7 Coronary heart disease
UKB-a:195 Sitting height ANASTROZOLE CYP19A1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12900487 7 Coronary heart disease
UKB-a:195 Sitting height LETROZOLE CYP19A1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs12900487 7 Coronary heart disease
UKB-a:195 Sitting height BRE-3 90Y MFGE8 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs8029053 7 Coronary heart disease
UKB-a:195 Sitting height FIGITUMUMAB IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height MECASERMIN IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height LINSITINIB IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height TEPROTUMUMAB IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height CIXUTUMUMAB IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height DALOTUZUMAB IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height MECASERMIN RINFABATE IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height AXL-1717 IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height GANITUMAB IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height AVE-1642 IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height BMS-754807 IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height ROBATUMUMAB IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height KW-2450 IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height XL-228 IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height PL-225B IGF1R -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs2871865 7 Coronary heart disease
UKB-a:195 Sitting height PENTOXIFYLLINE PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height ANAGRELIDE PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height DYPHYLLINE PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height DIPYRIDAMOLE PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height THEOPHYLLINE PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height CILOSTAZOL PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height MILRINONE PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height LEVOSIMENDAN PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height INAMRINONE PDE3A -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1444643 7 Coronary heart disease
UKB-a:195 Sitting height DUSIGITUMAB IGF2 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs35506085 7 Coronary heart disease
UKB-a:195 Sitting height EZOGABINE KCNQ1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1971929 7 Coronary heart disease
UKB-a:195 Sitting height TEDISAMIL KCNQ1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1971929 7 Coronary heart disease
UKB-a:195 Sitting height DALFAMPRIDINE KCNQ1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1971929 7 Coronary heart disease
UKB-a:195 Sitting height NERISPIRDINE KCNQ1 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs1971929 7 Coronary heart disease
UKB-a:195 Sitting height GEMCITABINE POLD3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs72979233 7 Coronary heart disease
UKB-a:195 Sitting height CYTARABINE POLD3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs72979233 7 Coronary heart disease
UKB-a:195 Sitting height FLUDARABINE PHOSPHATE POLD3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs72979233 7 Coronary heart disease
UKB-a:195 Sitting height CLOFARABINE POLD3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs72979233 7 Coronary heart disease
UKB-a:195 Sitting height TROXACITABINE POLD3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs72979233 7 Coronary heart disease
UKB-a:195 Sitting height TOSEDOSTAT C9orf3 -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs79634589 7 Coronary heart disease
UKB-a:195 Sitting height BEXAROTENE RXRA -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs10122419 7 Coronary heart disease
UKB-a:195 Sitting height ACITRETIN RXRA -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs10122419 7 Coronary heart disease
UKB-a:195 Sitting height ALITRETINOIN RXRA -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs10122419 7 Coronary heart disease
UKB-a:195 Sitting height ETRETINATE RXRA -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs10122419 7 Coronary heart disease
UKB-a:195 Sitting height SDX-101 RXRA -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs10122419 7 Coronary heart disease
UKB-a:195 Sitting height IRX-4204 RXRA -0.194858 FE IVW 0.67 1.280208e-13 0.026303 Tophits rs10122419 7 Coronary heart disease
843 Apolipoprotein B ATORVASTATIN APOE 0.320310 Penalised median 0.74 1.404539e-13 0.043309 DF + HF rs7412 7 Coronary heart disease
843 Apolipoprotein B EVOLOCUMAB PCSK9 0.320310 Penalised median 0.74 1.404539e-13 0.043309 DF + HF rs11591147 7 Coronary heart disease
843 Apolipoprotein B ALIROCUMAB PCSK9 0.320310 Penalised median 0.74 1.404539e-13 0.043309 DF + HF rs11591147 7 Coronary heart disease
843 Apolipoprotein B BOCOCIZUMAB PCSK9 0.320310 Penalised median 0.74 1.404539e-13 0.043309 DF + HF rs11591147 7 Coronary heart disease
843 Apolipoprotein B RALPANCIZUMAB PCSK9 0.320310 Penalised median 0.74 1.404539e-13 0.043309 DF + HF rs11591147 7 Coronary heart disease
UKB-a:64 Non-cancer illness code self-reported: pulmonary embolism +/- dvt FIBRINOLYSIN, HUMAN FGA -11.390210 FE IVW 1.00 2.104509e-13 1.551380 DF rs6050 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin HMG COA REDUCTASE INHIBITORS HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin SIMVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ROSUVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin PRAVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin FLUVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin PITAVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin CERIVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin LOVASTATIN HMGCR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12916 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin EVOLOCUMAB PCSK9 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs11591147 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ALIROCUMAB PCSK9 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs11591147 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin BOCOCIZUMAB PCSK9 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs11591147 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin RALPANCIZUMAB PCSK9 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs11591147 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin SULFONAMIDES TCF7L2 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs12243326 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin HMG COA REDUCTASE INHIBITORS LPA 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs10455872 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN APOE 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs429358 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN LDLR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs2569550 8 Coronary heart disease
UKB-a:176 Treatment/medication code: atorvastatin ATORVASTATIN LDLR 16.174022 FE IVW 0.70 2.256995e-13 2.205764 HF rs8106503 8 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading GEMCITABINE NT5C2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs11191580 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading BEPRIDIL CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs12258967 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading SULOCTIDIL CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs12258967 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading IMAGABALIN CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs12258967 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading ATAGABALIN CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs12258967 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading BEPRIDIL CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7911644 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading SULOCTIDIL CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7911644 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading IMAGABALIN CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7911644 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading ATAGABALIN CACNB2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7911644 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading TREBANANIB ANGPT2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs2979666 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading NESVACUMAB ANGPT2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs2979666 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading VANUCIZUMAB ANGPT2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs2979666 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading PBF-999 PDE10A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs4305701 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading DIPYRIDAMOLE PDE10A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs4305701 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading PENTOXIFYLLINE PDE10A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs4305701 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading METHAZOLAMIDE HLA-C 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs2524080 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading ALLOPURINOL HLA-C 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs2524080 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading TOSEDOSTAT ERAP2 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs1363976 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading SILDENAFIL PDE5A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs66887589 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading PENTOXIFYLLINE PDE5A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs66887589 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading TADALAFIL PDE5A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs66887589 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading VARDENAFIL PDE5A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs66887589 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading AVANAFIL PDE5A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs66887589 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading DIPYRIDAMOLE PDE5A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs66887589 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading UDENAFIL PDE5A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs66887589 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading PENTOXIFYLLINE PDE1A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs12693302 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading DIPYRIDAMOLE PDE1A 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs12693302 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading DALANTERCEPT BMP10 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs3812 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading NESIRITIDE NPR1 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs35479618 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading SEVOFLURANE KCNK3 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs34004783 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading ISOFLURANE KCNK3 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs34004783 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading DESFLURANE KCNK3 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs34004783 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading DOXAPRAM KCNK3 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs34004783 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN LISPRO INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN GLARGINE INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN DEGLUDEC INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN ASPART INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN DETEMIR INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN HUMAN INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN GLULISINE INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN PURIFIED PORK INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN SUSP ISOPHANE BEEF INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN PORK INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN SUSP ISOPHANE RECOMBINANT HUMAN INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN SUSP ISOPHANE SEMISYNTHETIC PURIFIED HUMAN INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN PURIFIED BEEF INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN LISPRO PROTAMINE RECOMBINANT INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN ASPART PROTAMINE RECOMBINANT INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN PEGLISPRO INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading LINSITINIB INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading INSULIN ZINC SUSP RECOMBINANT HUMAN INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading BMS-754807 INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading KW-2450 INSR 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7258382 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading CISPLATIN TP53 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs78378222 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading CYCLOPHOSPHAMIDE TP53 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs78378222 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading COLLAGENASE CLOSTRIDIUM HISTOLYTICUM COL4A1 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs650724 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading OCRIPLASMIN COL4A1 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs650724 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading COLLAGENASE CLOSTRIDIUM HISTOLYTICUM COL4A1 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7338606 7 Coronary heart disease
UKB-a:359 Diastolic blood pressure automated reading OCRIPLASMIN COL4A1 0.519485 Simple median 0.90 2.501108e-13 0.070979 HF rs7338606 7 Coronary heart disease
UKB-a:249 Weight NARNATUMAB MST1R 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs9843653 7 Coronary heart disease
UKB-a:249 Weight MK-8033 MST1R 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs9843653 7 Coronary heart disease
UKB-a:249 Weight MGCD-265 MST1R 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs9843653 7 Coronary heart disease
UKB-a:249 Weight FRESOLIMUMAB TGFB2 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs6684205 7 Coronary heart disease
UKB-a:249 Weight RIDAFOROLIMUS MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight PERHEXILINE MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight SAPANISERTIB MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight SF-1126 MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight APITOLISIB MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight LY-3023414 MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight AZD-2014 MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight GEDATOLISIB MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight DACTOLISIB MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease
UKB-a:249 Weight PF-04691502 MTOR 0.258414 RE IVW 0.76 5.969626e-13 0.034186 HF rs2791643 7 Coronary heart disease